The antibacterial activity of oregano essential oil (Origanum heracleoticum L.) against clinical strains of Escherichia coli and Pseudomonas aeruginosa
Author Information
Sienkiewicz M1, Wasiela M, Głowacka A.
1Zakład Mikrobiologii Lekarskiej i Sanitarnej, Wydział Wojskowo-Lekarski, Uniwersytet Medyczny w Łodzi, Plac Hallera 1, 90-647 Łódź.
Abstract
INTRODUCTION: The aim of this study was to investigate the antibacterial properties of oregano (Origanum heracleoticum L.) essential oil against clinical strains of Escherichia coli and Pseudomonas aeruginosa. The antibacterial activity of oregano essential oil was investigated against 2 tested and 20 clinical bacterial strains of Escherichia coli and 20 clinical strains o Pseudomonas aeruginosa comes from patients with different clinical conditions.
METHODS: The agar dilution method was used for microbial growth inhibition at various concentrations of oil. Susceptibility testing to antibiotics was carried out using disc-diffusion method.
RESULTS: The results of experiments showed that the tested oil was active against all of the clinical strains from both genus of bacteria, but strains of Escherichia coli were more sensitive to tested oil. Essential oil from Origanum heracleoticum L. inhibited the growth of Escherichia coli and Pseudomonas aeruginosa clinical strains with different patterns of resistance.
CONCLUSIONS: The obtained outcomes will enable further investigations using oregano essential oil obtained from Origanum heracleoticum L. as alternative antibacterial remedies enhancing healing process in bacterial infections and as an effective means for the prevention of antibiotic-resistant strain development.
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